Primary endodermal hemangiopericytoma/solitary fibrous tumor of the cervical spine: a case report and literature review

BMC Surgery

Jianbo Yu¹  Luyuan Zhang¹  Dongping Shu²  Liyun Wang²  Bin Huang³  Yumin Wang⁴ 

[1] Department of Neurosurgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China;Department of Neurosurgery, Shengzhou People’s Hospital (the First Affiliated Hospital of Zhejiang University Shengzhou Branch), Shengzhou, China;Department of Neurosurgery, Xinchang Hospital of Traditional Chinese Medicine, Shaoxing, China;Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, China;

关键词: Hemangiopericytoma;    Solitary fibrous tumor;    Primary cervical spine tumor;    Case report;   

DOI  :  10.1186/s12893-021-01399-6

来源: Springer

【 摘 要 】

BackgroundHemangiopericytoma (HPC), also known as solitary fibrous tumor (SFT), is a type of soft tissue sarcoma with a special aggressive behavior. The HPC/SFT is locally aggressive with possibility of late recurrence locally or distant extraneural metastasis. The most common location of this HPC/SFT is the lower extremities. The HPC/SFT in the central nervous system (CNS) is very rare, and compared with the brain, it is rarer in the spinal region. However, clinicians also lack an overall understanding of the diagnosis of HPC/SFT in the spinal cord.Case presentationIn this study, we report a rare case of primary cervical spine HPC/SFT in a 53-year-old woman. Two to three weeks before admission, she experienced pain and numbness in her left upper extremity. After computerized tomography (CT) and magnetic resonance imaging (MRI), a gross total resection was performed. Obvious neurological improvement was observed postoperatively. The pain and numbness in the patient's left upper limb were relieved subsequently. We then reviewed the literature on HPC/SFT, such as its clinical presentation, imaging characteristics, treatment, and follow-up.ConclusionsDiagnosis of HPC/SFT relies on magnetic resonance spectroscopy, enhanced CT, and MRI. Postoperative radiotherapy is strongly recommended to reduce the HPC/SFT recurrence. Immunohistochemical analysis can also help in the differential diagnosis. However; early and long-term follow-up is necessary for patients.

【 授权许可】

CC BY