PM2.5 exposure as a risk factor for type 2 diabetes mellitus in the Mexico City metropolitan area

BMC Public Health

Martha María Téllez-Rojo¹  Luis F. Bautista-Arredondo¹  Martín Romero-Martínez²  Stephen J. Rothenberg³  Jose L. Texcalac-Sangrador³  Allan C. Just⁴  Robert O. Wright⁴  Itai Kloog⁵  Olivia L. Chilian-Herrera⁶  Ruy López-Ridaura⁷  Marcela Tamayo-Ortiz⁸ 

[1] Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico;Center for Research in Surveys and Evaluation, National Institute of Public Health, Cuernavaca, Morelos, Mexico;Department of Environmental Health, Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico;Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA;Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer-Sheva, Israel;Homologous Normative Coordination, General Directorate, Mexican Social Security Institute, Mexico City, Mexico;National Center for Disease Prevention and Control Programs, Mexico City, Mexico;Occupational Health Research Unit, Mexican Social Security Institute, Av. Cuauhtémoc 330, Doctores, Cuauhtémoc, 06720, Mexico City, Mexico;

关键词: PM;    Particulate matter;    Air pollution;    Diabetes mellitus, type 2;    Mexico;   

DOI  :  10.1186/s12889-021-12112-w

来源: Springer

【 摘 要 】

BackgroundExposure to air pollution is the main risk factor for morbidity and mortality in the world. Exposure to particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5) is associated with cardiovascular and respiratory conditions, as well as with lung cancer, and there is evidence to suggest that it is also associated with type II diabetes (DM). The Mexico City Metropolitan Area (MCMA) is home to more than 20 million people, where PM2.5 levels exceed national and international standards every day. Likewise, DM represents a growing public health problem with prevalence around 12%. In this study, the objective was to evaluate the association between exposure to PM2.5 and DM in adults living in the MCMA.MethodsData from the 2006 or 2012 National Health and Nutrition Surveys (ENSANUT) were used to identify subjects with DM and year of diagnosis. We estimated PM2.5 exposure at a residence level, based on information from the air quality monitoring system (monitors), as well as satellite measurements (satellite). We analyzed the relationship through a cross-sectional approach and as a case - control study.ResultsFor every 10 μg/m3 increase of PM2.5 we found an OR = 3.09 (95% CI 1.17–8.15) in the 2012 sample. These results were not conclusive for the 2006 data or for the case - control approach.ConclusionsOur results add to the evidence linking PM2.5 exposure to DM in Mexican adults. Studies in low- and middle-income countries, where PM2.5 atmospheric concentrations exceed WHO standards, are required to strengthen the evidence.

【 授权许可】

CC BY