The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey

BMC Public Health

Felix Knauf¹  Tracy L. Rabin²  Katharina Kast³  Brooks Morgan⁴  Trishul Siddharthan⁴  Theresa Ermer⁵  Elke Schaeffner⁶  Bruce Kirenga⁷  Richard Munana⁸  Robert Kalyesubula⁸  Alex Kayongo⁸  Nora Anton⁹ 

[1]Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA

[2]Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany

[3]Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA

[4]Uganda Initiative for Integrated Management of Non-Communicable Diseases, Kampala, Uganda

[5]Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany

[6]Division of Pulmonary and Critical Care, School of Medicine, University of Miami, 1951 NW 7th Ave, Suite 2308, 33136, Miami, FL, USA

[7]Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA

[8]Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

[9]Institute of Public Health, Charité Universitätsmedizin Berlin, Berlin, Germany

[10]Makerere College of Health Sciences, Makerere University, Kampala, Uganda

[11]Makerere College of Health Sciences, Makerere University, Kampala, Uganda

[12]African Community Center for Social Sustainability (ACCESS), Nakaseke, Uganda

[13]World Health Summit c/o Charité Universitätsmedizin Berlin, Berlin, Germany

关键词: Non-communicable diseases;    Rural;    Low- and middle-income countries;   

DOI  :  10.1186/s12889-021-12123-7

来源: Springer

【 摘 要 】

BackgroundNon-communicable diseases (NCDs) are an increasing global concern, with morbidity and mortality largely occurring in low- and middle-income settings. We established the prospective Rural Uganda Non-Communicable Disease (RUNCD) cohort to longitudinally characterize the NCD prevalence, progression, and complications in rural Africa.MethodsWe conducted a population-based census for NCD research. We systematically enrolled adults in each household among three sub-counties of the larger Nakaseke Health district and collected baseline demographic, health status, and self-reported chronic disease information. We present our data on self-reported chronic disease, as stratified by age, sex, educational attainment, and sub-county.ResultsA total of 16,694 adults were surveyed with 10,563 (63%) respondents enrolled in the self-reported study. Average age was 37.8 years (SD = 16.5) and 45% (7481) were male. Among self-reported diseases, hypertension (HTN) was most prevalent (6.3%). 1.1% of participants reported a diagnosis of diabetes, 1.1% asthma, 0.7% COPD, and 0.4% kidney disease. 2.4% of the population described more than one NCD. Self-reported HTN was significantly higher in the peri-urban subcounty than in the other two rural sub-counties (p < 0.001); diagnoses for all other diseases did not differ significantly between sub-counties. Odds for self-reported HTN increased significantly with age (OR = 1.87 per 10 years of age, 95% CI 1.78–1.96). Male sex was associated with lower odds of reporting asthma (OR = 0.53, 95% CI 0.34–0.82) or HTN (OR = 0.31, 95% CI 0.26–0.40).ConclusionsThe RUNCD will establish one of the largest NCD patient cohorts in rural Africa. First analysis highlights the feasibility of systematically enrolling large numbers of adults living in a rural Ugandan district. In addition, our study demonstrates low levels of self-reported NCDs compared to the nation-wide established levels, emphasizing the need to better educate, characterize, and care for the majority of rural communities.

【 授权许可】

CC BY