Extranodal natural killer/T-cell lymphoma nasal type with extensive ocular tissue involvement: a case report

Diagnostic Pathology

Junjie Ye¹  Ailing Bian¹  Yang Jiang¹  Ruoan Han¹  Zhilan Meng²  Hao Chen³ 

[1] Department of Ophthalmology, Peking Union Medical College Hospital, Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, 100730, Beijing, China;Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 100730, Beijing, China;Department of Pathology, The Second Affiliated Hospital of Guangxi Medical University, 530005, Guangxi, China;

关键词: Extranodal natural killer/T-cell lymphoma;    Ocular tissue involvement;    Ciliary body;    Case report;   

DOI  :  10.1186/s13000-021-01167-3

来源: Springer

【 摘 要 】

BackgroundTo report a rare case of extranodal natural killer/T-cell lymphoma (ENKTL), nasal type related to extensive ocular tissue, including conjunctiva, ciliary body, vitreous and retina.Case presentationA 52-year-old woman who had been treated by radiotherapy for ENKTL, nasal type in the right nasal cavity presented with a dramatic deterioration of vision in right eye. Physical and accessory examination showed extensive ocular tissue related, including conjunctiva, ciliary body, vitreous and retina. Vitreous specimen and conjunctiva biopsy revealed the presence of ENKTL, nasal type in the right eye. She was treated with systemic and ophthalmic chemotherapy, her ocular symptoms significantly improved, and systemic condition remained stable 7 months after the diagnosis.ConclusionsExtranodal natural killer/T-cell lymphoma, nasal type is an aggressive disease and may relate extensive ocular tissue and course dramatic vision deterioration. It is important to observe ocular related and begin aggressive combined therapy as early as possible after diagnosis.

【 授权许可】

CC BY