European Journal of Medical Research | |
Vascular pythiosis caused by Pythium aphanidermatum: the first case report in Asia | |
Arsa Thammahong1  Navaporn Worasilchai1  Ariya Chindamporn1  Jaruwan Tiewsurin2  Rongpong Plongla3  Pannaporn Thongsuk3  Chusana Suankratay3  | |
[1] Department of Microbiology, Faculty of Medicine, Chulalongkorn University, 10330, Bangkok, Thailand;Division of Infectious Diseases, Department of Medicine, Buddhachinaraj Hospital, 65000, Phitsanulok, Thailand;Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, 10330, Bangkok, Thailand; | |
关键词: Pythiosis; Pythium; Pythium insidiosum; Pythium aphanidermatum; Case report; Asia; | |
DOI : 10.1186/s40001-021-00603-w | |
来源: Springer | |
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【 摘 要 】
BackgroundPythium, soil-borne plant pathogens, are in the class Oomycetes. They are not true fungi, but are related to diatom and algae. There are two human pathogens including P. insidiosum and P. aphanidermatum. To date, only one case of pythiosis caused by P. aphanidermatum has been reported. We present herein the first case of P. aphanidermatum vascular pythiosis in Asia.Case presentationA 47-year-old Thai woman, living in North Thailand, with ß thalassemia/hemoglobin E presented with acute recurrent arterial insufficiency of both legs. Emergent embolectomy with clot removal was performed. The pathology of the clot exhibited noncaseous granulomatous inflammation with many fungal hyphal elements. PCR identified P. aphanidermatum with 100% identity. Final diagnosis is vascular pythiosis. Unfortunately, the patient eventually expired after treatment with itraconazole, terbinafine, azithromycin, and doxycycline.ConclusionsTo date, only one case of pythiosis caused by P. aphanidermatum has been reported. We present herein the first case of P. aphanidermatum vascular pythiosis in Asia.
【 授权许可】
CC BY
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