Maternal-neonatal listeriosis

Virulence

Olivier Disson¹  Caroline Charlier²  Marc Lecuit² 

[1] Institut Pasteur, Biology of Infection Unit, Paris, Franc;Inserm U1117, Paris, Franc;Institut Pasteur, Biology of Infection Unit, Paris, Franc;Inserm U1117, Paris, Franc;Institut Pasteur, French National Reference Center and WHO Collaborating Center for Listeria, Paris, Franc;Hôpital Universitaire Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Institut Imagine, APHP, Paris, Franc;Université de Paris, Paris, Franc;

关键词: Listeriosis;    Listeria monocytogenes;    placenta;    pregnancy;    newborn;    fetus;    infection;   

DOI  :  10.1080/21505594.2020.1759287

来源: Taylor & Francis

【 摘 要 】

Listeriosis is a rare and severe foodborne infection caused by Listeria monocytogenes. It manifests as septicemia, neurolisteriosis, and maternal-fetal infection. In pregnancy, it may cause maternal fever, premature delivery, fetal loss, neonatal systemic and central nervous system infections. Maternal listeriosis is mostly reported during the 2nd and 3rd trimester of pregnancy, as sporadic cases or in the context of outbreaks. Strains belonging to clonal complexes 1, 4 and 6, referred to as hypervirulent, are the most associated to maternal-neonatal infections. Here we review the clinical, pathophysiological, and microbiological features of maternal-neonatal listeriosis.

【 授权许可】

CC BY