Edaravone prevents high glucose-induced injury in retinal Müller cells through thioredoxin1 and the PGC-1α/NRF1/TFAM pathway

Pharmaceutical Biology

Xinke Chen¹  Juanping Yin² 

[1] Department of Ophthalmology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, Chin;Department of Ophthalmology, The Fourth Hospital of Changsha, Changsha Hospital of Hunan Normal University, Changsha, Chin;

关键词: Diabetes;    retina;    ROS;    antioxidant;    apoptosis;    mitochondrial membrane potential;    oxidative products;    antioxidative enzymes;   

DOI  :  10.1080/13880209.2021.1972123

来源: Taylor & Francis

【 授权许可】

CC BY