Mutation on lysX from Mycobacterium avium hominissuis impacts the host–pathogen interaction and virulence phenotype

Virulence

Astrid Lewin¹  Greana Kirubakar¹  Volker Rickerts¹  Hubert Schäfer¹  Carsten Schwarz² 

[1]Division 16, Mycotic and Parasitic Agents and Mycobacteria, Robert Koch Institute, Berlin, German

[2]Pediatric Pneumology, Immunology and Intensive Care Medicine, Division of Cystic Fibrosis, Charité - Universitätsmedizin Berlin, Berlin, German

关键词: Virulence;    Mycobacterium avium hominissuis;    nontuberculous mycobacteria;    Galleria mellonella infection model;    multinucleated giant cells;    pathogenesis;    lys;    host-pathogen interaction;    inflammatory cytokines;   

DOI  :  10.1080/21505594.2020.1713690

来源: Taylor & Francis

【 授权许可】

CC BY