Kakonein restores diabetes‐induced endothelial junction dysfunction via promoting autophagy‐mediated NLRP3 inflammasome degradation

Journal of Cellular and Molecular Medicine

Yi Huang¹  Yanhong Zhang²  Ruifang Han³  Jiaying Liu³  Xiao Wang³  Jiaqi Jin⁴  Li Zhu⁴  Yang Chen⁴  Shaoxiang Xian⁵  Dawei Lian⁶ 

[1] Department of Stomatology, The School of Dental Medicine, Jinan University First Affiliated Hospital, Guangzhou, China;Department of Traditional Chinese Medicine, School of Medicine, Guangzhou First People’s Hospital, South China University of Technology, Guangzhou, China;Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China;School of Pharmaceutical, Guangzhou University of Chinese Medicine, Guangzhou, China;The First Affiliated Hospital and Postdoctoral Research Station, Guangzhou University of Chinese Medicine, Guangzhou, China;The First Affiliated Hospital and Postdoctoral Research Station, Guangzhou University of Chinese Medicine, Guangzhou, China;School of Pharmaceutical, Guangzhou University of Chinese Medicine, Guangzhou, China;

关键词: autophagy;    diabetes;    endothelial dysfunction;    kakonein;    NLRP3 inflammasome;   

DOI  :  10.1111/jcmm.16747

来源: Wiley

【 授权许可】

CC BY