HIF‐1α promotes the proliferation and migration of pulmonary arterial smooth muscle cells via activation of Cx43

Journal of Cellular and Molecular Medicine

Tao Hong¹  Li‐Jun Gan²  Xue‐Mei Lan²  Ren‐Jie Tan²  Qin Wang²  Fang‐Lin Zhang²  Zhang‐Jian Yang²  Le‐Ling Zhang²  Min Li²  Wei‐Fang Zhang³  Li‐Ping Jiang⁴  Chun‐Bo Zhang⁴  Xiao‐Jian Han⁵ 

[1] Department of Neurosurgery, First Affiliated Hospital of Nanchang University, Nanchang, China;Department of Pharmacology, School of Pharmaceutical Science, Nanchang University, Nanchang, China;Department of Pharmacy, The Second Affiliated Hospital of Nanchang University, Nanchang, China;Key Laboratory of Drug Targets and Drug Screening of Jiangxi Province, Nanchang, China;Department of Pharmacology, School of Pharmaceutical Science, Nanchang University, Nanchang, China;Key Laboratory of Drug Targets and Drug Screening of Jiangxi Province, Nanchang, China;Institute of Geriatrics, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China;Department of Neurology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China;

关键词: connexin 43;    hypoxia;    hypoxia‐induced pulmonary hypertension;    migration;    proliferation;    pulmonary artery smooth muscle cells;   

DOI  :  10.1111/jcmm.17003

来源: Wiley

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