CircTLK1 modulates sepsis‐induced cardiomyocyte apoptosis via enhancing PARP1/HMGB1 axis–mediated mitochondrial DNA damage by sponging miR‐17‐5p

Journal of Cellular and Molecular Medicine

Tao Jiang¹  Shuang‐Jie Li¹  Xiao‐Mei Qin¹  Wen‐Xian Ouyang¹  Yan‐Fang Tan¹  Ying Yu¹  Zheng‐Hui Xiao²  Yu Qiu² 

[1] Department of Hepatopathy, Hunan Children’s Hospital, Changsha, China;Emergency Center, Hunan Children’s Hospital, Changsha, China;

关键词: apoptosis;    circTLK1/miR‐17‐5p/PARP1/HMGB1 axis;    mitochondrial dysfunction;    mtDNA oxidative damage;    septic cardiomyopathy;   

DOI  :  10.1111/jcmm.16738

来源: Wiley

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