Youthful and age‐related matreotypes predict drugs promoting longevity

Aging Cell

Sean X. Liu¹  Elisabeth Jongsma¹  Collin Y. Ewald¹  Alexander Dakhovnik¹  Cyril Statzer¹  Pavlo Mozharovskyi²  Fred Zülli³  Franziska Wandrey³ 

[1] Department of Health Sciences and Technology, Institute of Translational Medicine, Eidgenössische Technische Hochschule Zürich, Schwerzenbach‐Zürich, Switzerland;LTCI, Telecom Paris, Institut Polytechnique de Paris, Palaiseau, France;Mibelle Biochemistry, Mibelle AG, Buchs, Switzerland;

关键词: aging;    CMap;    collagen;    drug repurposing;    extracellular matrix;    geroprotector;    GTEx;    longevity;    matrisome;    pharmacology;   

DOI  :  10.1111/acel.13441

来源: Wiley

【 授权许可】

CC BY