Oral submucous fibrosis stimulates invasion and epithelial‐mesenchymal transition in oral squamous cell carcinoma by activating MMP‐2 and IGF‐IR

Journal of Cellular and Molecular Medicine

Pei‐Ni Chen¹  Yu‐Chao Chang²  Shun‐Fa Yang³  Chiao‐Wen Lin⁴ 

[1] Clinical Laboratory, Chung Shan Medical University Hospital, Taichung, Taiwan;Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan;Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan;School of Dentistry, Chung Shan Medical University, Taichung, Taiwan;Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan;Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan;Institute of Oral Sciences, Chung Shan Medical University, Taichung, Taiwan;Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan;

关键词: epithelial‐mesenchymal transition;    insulin‐like growth factor‐1;    invasion;    oral cancer;    oral submucous fibrosis;   

DOI  :  10.1111/jcmm.16929

来源: Wiley

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