Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy

Aging Cell

H. Atakan Ekiz¹  Ryan M. O'Connell¹  Dennis K. Fix²  Alec M. Mckenzie²  Ziad S. Mahmassani²  Jonathan J. Petrocelli²  Micah J. Drummond³ 

[1]Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, Utah, USA

[2]Molecular Medicine Program, Department of Integrative Physiology and Nutrition, Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA

[3]Molecular Medicine Program, Department of Integrative Physiology and Nutrition, Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA

[4]Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, Utah, USA

关键词: glycolysis;    inflammation;    metabolomics;    scRNASeq;    single cell transcriptomics;   

DOI  :  10.1111/acel.13448

来源: Wiley

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