RNA polymerase II clusters form in line with surface condensation on regulatory chromatin

Molecular Systems Biology

Vasily Zaburdaev¹  Tim Klingberg¹  Andrei Yu Kobitski²  Weichun Zhang³  Roshan Prizak⁴  Amra Noa⁴  Irina Mamontova⁴  Marcel Sobucki⁴  Gerd Ulrich Nienhaus⁵  Lennart Hilbert⁶  Agnieszka Pancholi⁶ 

[1] Department of Biology, Friedrich‐Alexander‐Universität Erlangen‐Nürnberg, Erlangen, Germany;Max‐Planck‐Zentrum für Physik und Medizin, Erlangen, Germany;Institute of Applied Physics, Karlsruhe Institute of Technology, Karlsruhe, Germany;Institute of Applied Physics, Karlsruhe Institute of Technology, Karlsruhe, Germany;Institute of Nanotechnology, Karlsruhe Institute of Technology, Eggenstein‐Leopoldshafen, Germany;Institute of Biological and Chemical Systems—Biological Information Processing, Karlsruhe Institute of Technology, Eggenstein‐Leopoldshafen, Germany;Institute of Biological and Chemical Systems—Biological Information Processing, Karlsruhe Institute of Technology, Eggenstein‐Leopoldshafen, Germany;Institute of Applied Physics, Karlsruhe Institute of Technology, Karlsruhe, Germany;Institute of Nanotechnology, Karlsruhe Institute of Technology, Eggenstein‐Leopoldshafen, Germany;Department of Physics, University of Illinois at Urbana‐Champaign, Urbana, IL, USA;Zoological Institute, Department of Systems Biology and Bioinformatics, Karlsruhe Institute of Technology, Karlsruhe, Germany;Institute of Biological and Chemical Systems—Biological Information Processing, Karlsruhe Institute of Technology, Eggenstein‐Leopoldshafen, Germany;

关键词: active matter;    gene regulation;    nuclear organization;    super‐resolution microscopy;    transcriptional condensates;   

DOI  :  10.15252/msb.202110272

来源: Wiley

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CC BY