Aging impairs human bone marrow function and cardiac repair following myocardial infarction in a humanized chimeric mouse

Aging Cell

Jun Wu¹  Tina B. Marvasti¹  Lukasz Wlodarek¹  Faisal J. Alibhai¹  Anne Fu¹  Shu‐Hong Li¹  Ren‐Ke Li²  Terrence Yau²  Richard D. Weisel²  Robert J. Cusimano²  Maral Ouzounian² 

[1] Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada;Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada;Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada;

关键词: aging;    bone marrow transplant;    humanized mice;    myocardial infarction;   

DOI  :  10.1111/acel.13494

来源: Wiley

【 授权许可】

CC BY