Rational design of West Nile virus vaccine through large replacement of 3′ UTR with internal poly(A)

EMBO Molecular Medicine

Shun‐Li Zhan¹  Lei Gao¹  Shao‐Peng Yuan¹  Qiu‐Yan Zhang²  Xiao‐Dan Li²  Han‐Qing Ye²  Zhi‐Ming Yuan²  Bo Zhang²  Fang Yu²  Ya‐Nan Zhang²  Jing Liu²  Na Li²  Cheng‐Lin Deng²  Hong‐Qing Zhang²  Xiang‐Yue Zeng²  Pei‐Yong Shi³ 

[1] Beijing Shunlei Biotechnology Co. Ltd., Beijing, China;Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega‐Science, Chinese Academy of Sciences, Wuhan, China;University of Texas Medical Branch, Galveston, TX, USA;

关键词: flavivirus;    internal poly(A);    live‐attenuated vaccine;    UTR;    West Nile Virus;   

DOI  :  10.15252/emmm.202114108

来源: Wiley

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