(−)-Pentazocine Induces Visceral Chemical Antinociception, but not Thermal, Mechanical, or Somatic Chemical Antinociception, in μ-Opioid Receptor Knockout Mice

Molecular Pain

Masabumi Minami¹  Soichiro Ide²  Masamichi Satoh³  George R Uhl⁴  Ichiro Sora⁵  Kazutaka Ikeda⁶ 

[1] Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan;Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan;Research Project for Addictive Substances, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan;Department of Pharmacy, Yasuda Women's University, Hiroshima 731-0153, Japan;Molecular Neurobiology, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA;Molecular Neurobiology, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA;Division of Psychobiology Department of Neuroscience, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan;Research Project for Addictive Substances, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan;

关键词: Opioid receptor Knockout mice;    Pentazocine;    Antinociception;   

DOI  :  10.1186/1744-8069-7-23

来源: Sage Journals

【 授权许可】

CC BY