Vision, challenges and opportunities for a Plant Cell Atlas

eLife

Peter Denolf¹  Shao-shan Carol Huang²  Kenneth D Birnbaum²  Elsa H Quezada-Rodríguez³  Maite Saura-Sanchez⁴  Kerstin Kaufmann⁵  Luigi F Di Costanzo⁶  Marc Libault⁷  Fabio Gomez-Cano⁸  Toshihiro Obata⁹  Naomi Nakayama^1,10  Steven P Briggs^1,11  R Clay Wright^1,12  Jennifer AN Brophy^1,13  Alexander T Borowsky^1,14  Marisa S Otegui^1,15  Nicholas J Provart^1,16  Jamie Waese^1,17  Andrey V Malkovskiy^1,18  David W Ehrhardt^1,18  Suryatapa Ghosh Jha^1,18  Selena L Rice^1,18  Seung Y Rhee^1,18  Purva Karia^1,19  Moises Exposito-Alonso^2,20  Sagar Kumar^2,21  R Glen Uhrig^2,22  Gergo Palfalvi^2,23  Noah Fahlgren^2,24  Amir H Ahkami^2,25  Christopher R Anderton^2,25  Dae Kwan Ko^2,26  Benjamin J Cole^2,27  Andrew Farmer^2,28  Pinky Agarwal^2,29  Rajveer Singh^3,30  Klaas Van Wijk^3,31  Stefania Giacomello^3,32 

[1] BASF Seeds & Traits, Ghent, Belgium;Center for Genomics and Systems Biology, New York University, New York, United States;Ciencias Agrogenómicas, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México, León, Mexico;Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura, Facultad de Agronomía, Universidad de Buenos Aires, Buenos Aires, Argentina;Department for Plant Cell and Molecular Biology, Institute for Biology, Humboldt-Universitaet zu Berlin, Berlin, Germany;Department of Agricultural Sciences, University of Naples Federico II, Napoli, Italy;Department of Agronomy and Horticulture, University of Nebraska-Lincoln, Lincoln, United States;Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, United States;Department of Biochemistry, University of Nebraska-Lincoln, Madison, United States;Department of Bioengineering, Imperial College London, London, United Kingdom;Department of Biological Sciences, University of California, San Diego, San Diego, United States;Department of Biological Systems Engineering, Virginia Tech, Blacksburg, United States;Department of Biology, Stanford University, Stanford, United States;Department of Botany and Plant Sciences, University of California, Riverside, Riverside, United States;Department of Botany, University of Wisconsin-Madison, Madison, United States;Department of Cell and Systems Biology and the Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Canada;Department of Cell and Systems Biology/Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Canada;Department of Plant Biology, Carnegie Institution for Science, Stanford, United States;Department of Plant Biology, Carnegie Institution for Science, Stanford, United States;Department of Cell and Systems Biology, University of Toronto, Toronto, Canada;Department of Plant Biology, Carnegie Institution for Science, Stanford, United States;Department of Plant Biology, Carnegie Institution for Science, Tübingen, Germany;Department of Plant Breeding & Genetics, Mata Gujri College, Fatehgarh Sahib, Punjabi University, Patiala, India;Department of Science, University of Alberta, Edmonton, Canada;Division of Evolutionary Biology, National Institute for Basic Biology, Okazaki, Japan;Donald Danforth Plant Science Center, St. Louis, United States;Environmental Molecular Sciences Division, Pacific Northwest National Laboratory, Richland, United States;Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, United States;Joint Genome Institute, Lawrence Berkeley National Laboratory, Walnut Creek, United States;National Center for Genome Resources, Santa Fe, United States;National Institute of Plant Genome Research, New Delhi, India;School of Agricultural Biotechnology, Punjab Agricultural University, Ludhiana, India;School of Integrated Plant Science, Plant Biology Section, Cornell University, Ithaca, United States;SciLifeLab, KTH Royal Institute of Technology, Solna, Sweden;

关键词: location-to-function;    Plant Cell Atlas;    translational research;    4D imaging;    single-cell omics;    science forum;    A. thaliana;    Chlamydomonas reinhardtii;    Maize;   

DOI  :  10.7554/eLife.66877

来源: eLife Sciences Publications, Ltd

【 摘 要 】

With growing populations and pressing environmental problems, future economies will be increasingly plant-based. Now is the time to reimagine plant science as a critical component of fundamental science, agriculture, environmental stewardship, energy, technology and healthcare. This effort requires a conceptual and technological framework to identify and map all cell types, and to comprehensively annotate the localization and organization of molecules at cellular and tissue levels. This framework, called the Plant Cell Atlas (PCA), will be critical for understanding and engineering plant development, physiology and environmental responses. A workshop was convened to discuss the purpose and utility of such an initiative, resulting in a roadmap that acknowledges the current knowledge gaps and technical challenges, and underscores how the PCA initiative can help to overcome them.

【 授权许可】

CC BY