Neural mechanisms of modulations of empathy and altruism by beliefs of others’ pain

eLife

Shihui Han¹  Taoyu Wu¹ 

[1] School of Psychological and Cognitive Sciences, PKU-IDG/MGovern Institute for Brain Research, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China;

关键词: belief;    empathy;    altruism;    pain;    EEG;    fMRI;    Human;   

DOI  :  10.7554/eLife.66043

来源: eLife Sciences Publications, Ltd

【 摘 要 】

Perceived cues signaling others’ pain induce empathy which in turn motivates altruistic behavior toward those who appear suffering. This perception-emotion-behavior reactivity is the core of human altruism but does not always occur in real-life situations. Here, by integrating behavioral and multimodal neuroimaging measures, we investigate neural mechanisms underlying modulations of empathy and altruistic behavior by beliefs of others’ pain (BOP). We show evidence that lack of BOP reduces subjective estimation of others’ painful feelings and decreases monetary donations to those who show pain expressions. Moreover, lack of BOP attenuates neural responses to their pain expressions within 200 ms after face onset and modulates neural responses to others’ pain in the insular, post-central, and frontal cortices. Our findings suggest that BOP provide a cognitive basis of human empathy and altruism and unravel the intermediate neural mechanisms.

【 授权许可】

CC BY