A Three-Dimensional-reconstruction-based study on the ocular volume of Chinese children with high myopia

BMC Ophthalmology

Chun Lung¹  Hongwei Deng²  Yanni Jiang³  Xiaodan Jiang³  Shuang Li³  Mingyue Wang³  Fanyin Wang³ 

[1] CAS-Medi-Vision Company Limited, Zhuhai, China;Department of Strabismus & Pediatric Ophthalmology, Shenzhen Eye Hospital affiliated to Jinan University, The School of Optometry of Shenzhen University, No.18 of Zetian Street, Futian District, 518000, Shenzhen, China;Ophthalmology Department, Shenzhen Shekou People’s Hospital, No.36 Gongye 7th Road, Shekou, Nanshan District, 518067, Shenzhen, China;

关键词: Children;    High myopia;    Ocular volume;    Computed tomography;   

DOI  :  10.1186/s12886-021-02078-z

来源: Springer

【 摘 要 】

BackgroundHighly myopic eyes differ in morphology from emmetropic eyes, and the correct estimation of the vitreous volume is difficult. To explore an effective method to estimate ocular volume using refractive factors in children.MethodsThis is a retrospective study of children with high myopia who visited the Shenzhen Shekou People’s Hospital (July-December 2018) before undergoing posterior scleral reinforcement surgery. Data on refractive factors and ocular 3D reconstruction imaging based on high-end CT were collected for linear correlation and linear regression analyses.ResultsTen patients (20 eyes) were included. There are nine males and one female. They were 4 to 12 years of age. The spherical equivalent ranges from + 0.25 to -20.00 D. The cylindrical equivalent ranges from − 0.50 to -6.25 D. The AL(axial length, AL) ranges from 21.78 to 33.90 mm. The corneal curvature (mean) ranges from 42.44 to 46.75. The 3D reconstruction of the CT images shows that the ocular volume ranges from 4.591 to 10.988 ml. The ocular volume of the 20 eyes decreases with the increase of diopter and total curvature, both presenting a linear trend, with the Pearson correlation coefficients being − 0.776 (P < 0.001) and − 0.633 (P = 0.003), respectively. The ocular volume of the 20 eyes increases with the increasing AL, also presenting a linear trend, with the Pearson correlation coefficient being 0.939 (P < 0.001).ConclusionsIn children, the ocular volume is negatively and linearly correlated with the diopter and curvature, and positively and linearly correlated with the AL.

【 授权许可】

CC BY