The effect of probiotics on bowel movement and metabolic parameters in schizophrenia patients: a retrospective chart review

Bioscience of Microbiota, Food and Health

article

Masaru NAKAMURA¹  Takahiko NAGAMINE¹ 

[1] Sunlight Brain Research Center

关键词: constipation;    metabolic parameters;    probiotics;    schizophrenia patients;   

DOI  :  10.12938/bmfh.2020-022

学科分类：生物科学（综合）

来源: Nihon Bifizusukin Senta / Japan Bifidus Foundation

【 摘 要 】

Schizophrenia patients have a higher prevalence of constipation and metabolic disorders due to the disease itself and antipsychotics which possess anticholinergic and antihistaminergic effects [1]. Probiotics have the benefits of regulating bowel movement and ameliorating metabolic disorders [2]. However, limited inferences can be made regarding the efficacy of probiotics in schizophrenia patients. To investigate the effect of probiotics on bowel movement and metabolic parameters in schizophrenia patients, we conducted a retrospective chart review of schizophrenia inpatients who were treated with a combination probiotic including Streptococcus faecalis 2 × 108 CFU/day, Bacillus mesentericus 1 × 107 CFU/ day, and Clostridium butyricum 5 × 107 CFU/day for constipation for more than two months.

【 授权许可】

CC BY