Metal-Organic Frameworks for Bioimaging: Strategies and Challenges

Nanotheranostics

article

Zhenbao Liu¹  Ting Jiang³  Yanfei Liu³ 

[1] Department of Pharmaceutics, Xiangya School of Pharmaceutical Sciences, Central South University;Molecular Imaging Research Center of Central South University;Department of Pharmaceutical Engineering, College of Chemistry and Chemical Engineering, Central South University

关键词: Metal-organic frameworks;    Optical bioimaging;    Magnetic resonance imaging (MRI);    Computed tomography;   

DOI  :  10.7150/ntno.63458

学科分类：大气科学

来源: Ivyspring International Publisher

【 摘 要 】

Metal-organic frameworks (MOFs), composited with metal ions and organic linkers, have become promising candidates in the biomedical field own to their unique properties, such as high surface area, pore-volume, tunable pore size, and versatile functionalities. In this review, we introduce and summarize the synthesis and characterization methods of MOFs, and their bioimaging applications, including optical bioimaging, magnetic resonance imaging (MRI), computed tomography (CT), and multi-mode. Furthermore, their bioimaging strategies, remaining challenges and future directions are discussed and proposed. This review provides valuable references for the designing of molecular bioimaging probes based on MOFs.

【 授权许可】

CC BY-NC