Fifty Years of Witnessing Biomedical Science Developments

Iranian Journal of Medical Sciences

article

Manica Negahdaripour¹ 

[1] Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences;Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences

DOI  :  10.30476/ijms.2020.47043

学科分类：内科医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

On the occasion of the 50th anniversary of the Iranian Journal of Medical Sciences (IJMS), a review on the major progresses in biomedical sciences in the past fifty years could remind the journey that have revolutionized the disease diagnosis and treatment during which IJMS have been served as a companion to the scientific community. Much of the accomplishments in biomedicine in the last 50 years, is in fact based on the success of Watson and Crick in solving the double helix structure of deoxyribonucleic acid (DNA) more than half a century ago. About twenty years later, in 1972, Paul Berg created the first recombinant DNA molecule via combining genes from two different organisms, taking advantage of the restriction enzyme discovery in 1970. Later, in 1978, Werner Arber, Daniel Nathans, and Hamilton O. Smith jointly received the Nobel Prize in Physiology or Medicine for discovering restriction enzymes and their application to problems of molecular genetics. In 1972, Godfrey Hounsfield, a British engineer, and Allan Cormack, a South Africa-born physicist working in the US, independently invented Computed Tomography (CT) scan diagnostic machine and technique, which brought them the Nobel prize for Physiology or Medicine in 1979. Small pox eradication in1977, could be named as one of the most outstanding achievements in medical history, which was accomplished through vaccination. In 1977, Frederick Sanger and Walter Gilbert, who separately worked on developing rapid methods for DNA sequencing, won half of the 1980 Nobel prize in Chemistry. The first clinical whole-body magnetic-resonance imaging (MRI) scan was also performed in 1980. Two years later, the teams of Robert Weinberg, Michael Wigler, and Mariano Barbacid reported the first human oncogenes and proved that tumors are the result of mutations in the genome.

【 授权许可】

CC BY-ND