Long-term medication reduction in controlled glaucoma with iTrack ab-interno canaloplasty as a standalone procedure and combined with cataract surgery

Therapeutic Advances in Ophthalmology

article

Mahmoud A. Khaimi¹ 

[1] Department of Neo - natology and Pediatric Intensive Care Medicine, Center for Pediatrics, University Hospital Bonn

关键词: ab-interno canaloplasty;    glaucoma;    iTrack;    MIGS;    primary open-angle glaucoma;    Schlemm’s canal;    viscodilation;   

DOI  :  10.1177/25158414211045751

学科分类：社会科学、人文和艺术（综合）

来源: Gdansk University Of Physical Education And Sport

【 摘 要 】

Purpose: To evaluate the long-term effectiveness of iTrack (Nova Eye Medical, Fremont, USA) ab-interno canaloplasty performed as a standalone procedure, or combined with cataract surgery, in reducing antiglaucoma medication dependence and maintaining intraocular pressure within target range in patients with controlled primary open-angle glaucoma. Methods: This is a retrospective, single-center, case series study of patients who underwent iTrack ab-interno canaloplasty as a standalone procedure (n=34) or in combination with cataract surgery (n=11). Eyes with controlled mild or moderate glaucoma (intraocular pressure ⩽17mmHg) were included; those with prior glaucoma surgeries were excluded. The primary outcome was the mean reduction in glaucoma medication and the secondary outcome was the maintenance of controlled intraocular pressure postoperatively. Results: A total of 35 patients (45 eyes) with a mean age of 73±9.7years were included in the study. For all eyes, a significant decrease (61%) in the mean number of medications was seen at 36months (1.89±0.93 versus 0.60±0.82; p<0.001), with 56% (14/25) of eyes medication free. No significant difference was observed in the reduction of medication use whether iTrack was performed with or without cataract surgery at 12 and 36 months. Mean baseline intraocular pressure of 14.42±2.2mmHg for all eyes was maintained at the 12-, 24-, and 36-month follow-up visits (14.6±3.65, 15.06±2.26, and 14.19±2.91, respectively), with no significant difference between the two groups (p=0.08). Conclusion: The iTrack ab-interno canaloplasty significantly reduced medication dependency and maintained intraocular pressure within target range in patients with controlled mild or moderate primary open-angle glaucoma, while showing a good safety profile, both as a standalone procedure or in combination with cataract surgery.

【 授权许可】

CC BY|CC BY-NC