A quadratic model captures the human V1 response to variations in chromatic direction and contrast

eLife

Geoffrey K Aguirre¹  David Brainard²  Michael A Barnett² 

[1] Department of Neurology, University of Pennsylvania, Philadelphia, United States;Department of Psychology, University of Pennsylvania, Philadelphia, United States;

关键词: color vision;    fMRI;    V1;    isoresponse contour;    forward model;    contrast response function;    Human;   

DOI  :  10.7554/eLife.65590

来源: eLife Sciences Publications, Ltd

【 摘 要 】

An important goal for vision science is to develop quantitative models of the representation of visual signals at post-receptoral sites. To this end, we develop the quadratic color model (QCM) and examine its ability to account for the BOLD fMRI response in human V1 to spatially uniform, temporal chromatic modulations that systematically vary in chromatic direction and contrast. We find that the QCM explains the same, cross-validated variance as a conventional general linear model, with far fewer free parameters. The QCM generalizes to allow prediction of V1 responses to a large range of modulations. We replicate the results for each subject and find good agreement across both replications and subjects. We find that within the LM cone contrast plane, V1 is most sensitive to L-M contrast modulations and least sensitive to L+M contrast modulations. Within V1, we observe little to no change in chromatic sensitivity as a function of eccentricity.

【 授权许可】

CC BY