Coronary artery aneurysms in children is not always Kawasaki disease: a case report on Takayasu arteritis

BMC Rheumatology

Jane W. Newburger¹  Audrey Dionne¹  Kevin G. Friedman¹  Michelle Lee²  MaryBeth Son³  Esra Meidan³ 

[1] Department of Cardiology, Boston Children’s Hospital, 300 Longwood Avenue- Farley 2, 02115, Boston, MA, USA;Division of Immunology, Boston Children’s Hospital, Boston, USA;Department of Pediatrics, Harvard Medical School, Boston, MA, USA;Department of Cardiology, Boston Children’s Hospital, 300 Longwood Avenue- Farley 2, 02115, Boston, MA, USA;Department of Pediatrics, Harvard Medical School, Boston, MA, USA;Division of Immunology, Boston Children’s Hospital, Boston, USA;

关键词: Kawasaki disease;    Takayasu’s arteritis;    Coronary artery aneurysm;    Case report;   

DOI  :  10.1186/s41927-021-00197-0

来源: Springer

【 摘 要 】

BackgroundCoronary artery (CA) aneurysms in children are a rare but potentially life-threatening finding and are highly associated with Kawasaki disease (KD).Case presentationWe describe a four-year-old female with a vasculitis and CA aneurysms. She had a prolonged course with recurrent fever and systemic inflammation several times upon discontinuation of steroid treatment. Due in part to the CA aneurysms, she initially was diagnosed with KD but due to the unusual clinical course, further evaluation was performed. Abdominal and chest MRI/A revealed diffuse aortitis suggestive of a large vessel vasculitis, specifically Takayasu arteritis. With treatment targeted for Takayasu arteritis, there was resolution of fever and inflammation and the CA aneurysms improved.ConclusionsThis case demonstrates the utility in broadening the differential diagnosis in cases of presumed KD with CA involvement in which the clinical course is atypical for KD.

【 授权许可】

CC BY