Prevalence of strongyloidiasis in Peru: systematic review and meta-analysis

BMC Infectious Diseases

Eva de-Miguel-Balsa¹  José-Manuel Ramos-Rincón²  Miguel Górgolas-Hernández-Mora³  Luis-Alfredo Espinoza-Venegas⁴  Martín Casapía-Morales⁵  Sonia Ortiz-Martínez⁶  Viviana-Vanessa Pinedo-Cancino⁷  María-Esteyner Vásquez-Chasnamote⁸  Katty-Madeleine Arista-Flores⁹  Olga-Nohelia Gamboa-Paredes⁹ 

[1] Clinical Medicine Department, University Miguel Hernández of Elche, Ctra N-332, 03550 Sant Joan d’Alacant, Alicante, Spain;Intensive Care Unit, General University Hospital of Elche, Alicante, Spain;Clinical Medicine Department, University Miguel Hernández of Elche, Ctra N-332, 03550 Sant Joan d’Alacant, Alicante, Spain;Internal Medicine Service, General University Hospital of Alicante-ISABIAL, Alicante, Spain;Infectious Disease Division, University Hospital Foundation Jiménez Díaz, Madrid, Spain;Medicine Department, Autonomous University of Madrid, Madrid, Spain;Infectious Diseases and Tropical Medicine Service, Loreto Regional Hospital, Iquitos, Peru;Infectious Diseases and Tropical Medicine Service, Loreto Regional Hospital, Iquitos, Peru;Medical Department, Amazon Rainforest Civil Association, Iquitos, Peru;School of Medicine, National University of the Peruvian Amazon, Iquitos, Peru;Medical Practice El Ballestero, Health Service of Castilla La Mancha, Albacete, Spain;Molecular Biology and Immunology Laboratory of the Specialized Unit of LIPNAA-CIRNA, National University of the Peruvian Amazon, Iquitos, Peru;Natural Resources Research Center. National University of the Peruvian Amazon, Iquitos, Peru;Research Assistant. Amazon Rainforest Civil Association, Iquitos, Peru;

关键词: Strongyloides stercoralis;    Serology;    Seroprevalence;    Prevalence;    Peru;   

DOI  :  10.1186/s12879-021-06441-9

来源: Springer

【 摘 要 】

BackgroundStrongyloidiasis is a disease of great public health significance, caused by the parasitic nematodes Strongyloides stercoralis, Strongyloides fuelleborni, and Strongyloides fuelleborni subsp. kellyi. This systematic review and meta-analysis aimed to assess the prevalence of Strongyloides stercoralis infection in Peru.MethodsThe review was based on a literature search in PubMed, SciELO and Google Scholar using the key words or root words “strongyl*” AND “Peru” on 15 July 2020. Eligible studies were published from 1 January 1981 to 15 July 2020 and written in English, Spanish, Italian, or French.ResultsWe included 21 papers in the analysis. Studies were heterogeneous in terms of study population and diagnostic methods (e.g. Baermann technique, agar, Dancescu or charcoal cultures, serology, string capsule). Prevalence of S. stercoralis ranged from 0.3 to 45%. The pooled proportion of Strongyloides in the general population was 7.34% (95% CI 4.97 to 10.13%). Half the studies were designed to detect parasites in general. In studies designed to detect S. stercoralis, the most widely used diagnostic method was the Baermann technique.ConclusionPrevalence of S. stercoralis in Peru was high but varied by geographic area, techniques for stool examination, and participant characteristics.

【 授权许可】

CC BY