Comparative study of Amsel’s criteria and Nugent scoring for diagnosis of bacterial vaginosis in a tertiary care hospital, Nepal

BMC Infectious Diseases

Shyam Kumar Mishra¹  Keshab Parajuli¹  Rajshree Bhujel¹  Santosh Kumar Yadav²  Kesang Diki Bista³ 

[1] Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal;Department of Microbiology, Rajarshi Janak University, Janakpurdham, Nepal;Department of Obstetrics and Gynecology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal;

关键词: Amsel’s criteria;    Bacterial vaginosis;    Nugent scoring;    Vaginal discharge;   

DOI  :  10.1186/s12879-021-06562-1

来源: Springer

【 摘 要 】

BackgroundThe most common pathological cause of abnormal vaginal discharge in reproductive-aged women is bacterial vaginosis (BV). Amsel’s criteria and Nugent scoring systems are commonly employed approaches for the diagnosis of BV. Despite the Nugent scoring system being the gold standard method for diagnosing BV, Amsel’s criteria are generally preferred in clinical setup owing to the fact Nugent scoring requires considerable time and expert microscopist. This study was conducted to determine the diagnostic value of Amsel’s criteria by comparing it with the Nugent scoring system.MethodsThis was a descriptive cross-sectional study conducted at Tribhuvan University Teaching Hospital, Nepal from October 2016 to September 2017. Vaginal specimens were collected from a total of 141 women presenting with abnormal vaginal discharge. The sensitivity, specificity, positive predictive value, and negative predictive value of Amsel’s criteria were calculated, and each component of Amsel’s criteria was compared to the Nugent scoring system.ResultsThe sensitivity, specificity, positive predictive value, and negative predictive value of Amsel’s criteria were 50%, 98.2%, 87.5%, and 88.8% respectively. The clue cells showed 100% specificity and vaginal discharge with pH > 4.5 had 89.3% sensitivity while compared with Nugent’s scoring system.ConclusionsAmsel’s criteria can be used as an adjunct method to Nugent scoring for the diagnosis of BV in the hands of skilled manpower in resources limited countries. The presence of clue cell and positive whiff test of Amsel’s criteria shows good match with Nugent’s score.

【 授权许可】

CC BY