Impact of Pharmacist-Led Interventions on Diabetes Management at a Community Pharmacy in Pakistan: A Randomized Controlled Trial

Inquiry: a journal of medical care organization, provision and financing

article

Muhammad Abubakar¹  Muhammad Atif¹ 

[1] Department of Pharmacy Practice, Faculty of Pharmacy, The Islamia University of Bahawalpur;Department of Pharmacy Practice, Faculty of Pharmacy and Health Sciences, University of Balochistan

关键词: type 2 diabetes mellitus;    community pharmacists;    glycemic control;    intervention;    randomized control trial;    Pakistan;   

DOI  :  10.1177/00469580211036283

来源: Sage Journals

【 摘 要 】

Purpose: The study aimed to determine the impact of pharmacist-led interventions on diabetes management at a communitypharmacy in Pakistan.Methods: A one-month follow-up, randomized controlled trial (RCT) was carried out between December 1, 2016 and June 30,2017. Sampling population consisted of patients diagnosed with type 2 diabetes mellitus (T2DM). The study population wasrandomized to a control group or an intervention group to determine the impact of a community pharmacist intervention onglycemic control fasting blood glucose (FBG) and random blood glucose (RBG), medication adherence (MMAS), and healthrelated quality of life (HRQoL) (EQ-5D-3L). Both non-pharmacological and pharmacological interventional tools were used thatconsist of array of charts and verbal communication by pharmacist. Outcomes for continuous variables were analyzed usingpaired sample t-test for time effect and one sample t-test to evaluate the study group effect. Independent sample t-test was usedto compare each independent variable with dependent variable. A P-value of <.05 was considered statistically significant.Results: The control and intervention groups showed significant improvement (P-value < .05) in glycemic control, medication adherence, and HRQoL. However, the difference between the control and intervention groups was not statistically significant in terms ofblood glucose levels and HRQoL (time trade off, TTO). There was a clinically significant association between pharmacist intervention andpredefined glycemic control among the study participants (FBG: P-value < .001 and RBG: P-value = .04). A clinically significant associationwas also found between pharmacist intervention and medication adherence at the end of the trial compared with baseline values (P-value <.001). Similarly, a clinically significant association was found between pharmacist intervention and predefined HRQoL [TTO: P-value = .002and EQ-VAS: P-value = .001].Conclusion: A significant proportion of T2DM patients in the intervention group achieved predefined glycemic control,medication adherence, and health related quality of life.

【 授权许可】

Unknown