Brazilian Protocol for Sexually Transmitted Infections 2020: syphilis diagnostic tests

Sociedade Brasileira de Medicina Tropical. Revista

article

Pâmela Cristina Gaspar¹  Álisson Bigolin²  José Boullosa Alonso Neto¹  Esdras Daniel dos Santos Pereira¹  Maria Luiza Bazzo² 

[1] Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis, Brasil. Universidade de Brasília, Programa de Pós-Graduação em Saúde Coletiva;Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis, Brasil. Universidade Federal de Santa Catarina, Laboratório de Biologia Molecular

关键词: Syphilis;    Neurosyphilis;    Congenital syphilis;    Diagnosis;   

DOI  :  10.1590/0037-8682-630-2020

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

The recommendations for diagnostic tests for investigating syphilis are part of the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections and the Technical Manual for Syphilis Diagnosis, published by the Brazilian Ministry of Health. These recommendations were developed based on scientific evidence and discussions with a panel of experts. This article presents direct tests to detect Treponema pallidum in lesions and algorithms that combine treponemal and nontreponemal antibody tests to assist in syphilis diagnosis, with the aim of contributing to the efforts of health service managers and health professionals in qualifying health care. The article also covers the use of non-treponemal tests to investigate neurosyphilis and guidelines for interpreting non-treponemal antibody titers in monitoring the treatment and diagnosis of congenital syphilis, as well as prospects for innovations in diagnosis. The critical role of rapid immunochromatographic treponemal tests for public health and for addressing syphilis is also highlighted.

【 授权许可】

CC BY