Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region

Sociedade Brasileira de Medicina Tropical. Revista

article

Edlainny Araujo Ribeiro¹  Ana Cristina Gales²  Ana Paula Streling de Oliveira²  Danilo Dias Coelho³  Rodrigo Alves de Oliveira³  Irmtraut Araci Hoffmann Pfrimer¹  José Rodrigues do Carmo Filho¹ 

[1] Pontifícia Universidade Católica de Goiás, Programa de Pós-Graduação Stricto Sensu em Ciências Ambientais e Saúde;Universidade Federal de São Paulo, Laboratório Especial de Microbiologia Clínica;Hospital Regional Público do Araguaia

关键词: Acinetobacter baumannii;    Carbapenem resistance;    Carbapenemase;    bla OXA-23;    Gram-negative bacilli;   

DOI  :  10.1590/0037-8682-0087-2020

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Introduction: In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region. Methods: The isolates were identified by MALDITOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE). Results: Only 10 (55.6%) isolates harbored the gene blaOXA-23. PFGE analysis revealed that these isolates belong to a single clone. Conclusions: This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced.

【 授权许可】

CC BY