Antifungal activity of liriodenine on agents of systemic mycoses, with emphasis on the genus Paracoccidioides

Journal of venomous animals and toxins

article

Adriele Dandara Levorato Vinche¹  Iván de- la-Cruz-Chacón²  Alma Rosa González-Esquinca²  Julhiany de Fátima da Silva¹  Gisela Ferreira³  Daniela Carvalho dos Santos³  Hans Garcia Garces³  Daniela Vanessa Moris de Oliveira⁴  Camila Marçon¹  Ricardo de Souza Cavalcante¹  Rinaldo Poncio Mendes¹ 

[1] Department of Tropical Disease and Imaging Diagnosis, Botucatu Medical School, São Paulo State University (UNESP);Universidad de Ciencias y Artes de Chiapas;Institute of Biosciences of Botucatu, São Paulo State University (UNESP);Universidade do Oeste Paulista (Unoeste)

关键词: Liriodenine;    Paracoccidioidomycosis;    Systemic mycosis;    Antifungal compounds;    Antimicrobial compounds;    Medicinal plants;   

DOI  :  10.1590/1678-9199-JVATITD-2020-0023

学科分类：药理学

来源: BioMed Central

【 摘 要 】

Background: Endemic systemic mycoses remain a health challenge, since these opportunistic diseases are increasingly infecting immunosuppressed patients. The simultaneous use of antifungal compounds and other drugs to treat infectious or non-infectious diseases has led to several interactions and undesirable effects. Thus, new antifungal compounds should be investigated. The present study aimed to evaluate the activity of liriodenine extracted from Annona macroprophyllata on agents of systemic mycoses, with emphasis on the genus Paracoccidioides .

【 授权许可】

CC BY