An Ultrasound Model to Predict the Short-Term Effects of Endovascular Stent Placement in the Treatment of Carotid Artery Stenosis

Frontiers in Cardiovascular Medicine

article

Sheng-Jiang Chen¹  Rui-Rui Liu¹  Yi-Ran Shang¹  Yu-Juan Xie¹  Xiao-Han Guo¹  Meng-Jiao Huang¹  Xiao-Feng Yang¹  Qi-Zhi Fu²  Ji-Sheng Qi²  Dong-Yan Shen³  Jia-Yan Li⁴ 

[1] Department of Ultrasound, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology;Department of Neurology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology;Department of Vascular Surgery, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology;Department of Ultrasound, Luoyang Dongfang Hospital, The Third Affiliated Hospital of Henan University of Science and Technology

关键词: carotid artery;    neurological deficit score;    stent placement;    ultrasound;    model;   

DOI  :  10.3389/fcvm.2020.607367

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Purpose: The present study aimed to explore the predictive ability of an ultrasound linear regression equation in patients undergoing endovascular stent placement (ESP) to treat carotid artery stenosis-induced ischemic stroke. Methods: Pearson's correlation coefficient of actual improvement rate (IR) and 10 preoperative ultrasound indices in the carotid arteries of 64 patients who underwent ESP were retrospectively analyzed. A predictive ultrasound model for the fitted IR after ESP was established. Results: Of the 10 preoperative ultrasound indices, peak systolic velocity (PSV) at stenosis was strongly correlated with postoperative actual IR ( r = 0.622; P < 0.01). The unstable plaque index (UPI; r = 0.447), peak eccentricity ratio ( r = 0.431), and plaque stiffness index (β; r = 0.512) moderately correlated with actual IR ( P < 0.01). Furthermore, the resistance index ( r = 0.325) and the dilation coefficient ( r = 0.311) weakly correlated with actual IR ( P < 0.05). There was no significant correlation between actual IR and the number of unstable plaques, area narrowing, pulsatility index, and compliance coefficient. In combination, morphological, hemodynamic, and physiological ultrasound indices can predict 62.39% of neurological deficits after ESP: fitted IR = 0.9816 – 0.1293β + 0.0504UPI – 0.1137PSV. Conclusion: Certain carotid ultrasound indices correlate with ESP outcomes. The multi-index predictive model can be used to evaluate the effects of ESP before surgery.

【 授权许可】

CC BY