Recurrent Pericarditis in Children and Adolescents

Frontiers in Pediatrics

article

Enrico Tombetti¹  Teresa Giani²  Antonio Brucato¹  Rolando Cimaz⁴ 

[1] Department of Medicine, Azienda Socio Sanitaria Territoriale (ASST) Fetebenefratelli-Sacco and Department of “Biomedical and Clinical Sciences Luigi Sacco”, Milan University;Rheumatology Unit, Department of Pediatrics, Anna Meyer Children's Hospital, University of Florence;Department of Medical Biotechnology, University of Siena;Department of Clinical Sciences and Community Health, University of Milan;Azienda Socio Sanitaria Territoriale (ASST) G.Pini

关键词: pericarditis;    myopericarditis;    children;    adolescents;    pediatric;    autoinflammatory diseases;   

DOI  :  10.3389/fped.2019.00419

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Recurrent pericarditis (RP) is a clinical syndrome characterized by recurrent attacks of acute pericardial inflammation. Prognosis quoad vitam is good, although morbidity might be significant, especially in children and adolescents. Multiple potential etiologies result in RP, in the vast majority of cases through autoimmune or autoinflammatory mechanisms. Idiopathic RP is one of the most frequent diagnoses, that requires the exclusion of all known etiologies. Therapeutic advances in the last decade have been significant with the recognition of the effectiveness of anti IL1 therapy, but a correct diagnostic and therapeutic algorithm is of key importance. Unfortunately, most of evidence comes from studies in adult patients. Here we review the etiopathogenesis, diagnosis and management of RP in pediatric patients.

【 授权许可】

CC BY