Sex-Specific Differences in Related Indicators of Blood Pressure in School-Age Children With Overweight and Obesity: A Cross-Sectional Study

Frontiers in Pediatrics

article

Hongmei He¹  Huishen Pang¹  Shaoping Ji²  Lu Zhang¹  Xiangqian Guo¹  Shujun Yang⁵  Na Qiu¹  Ling Qiao¹  Yong Ding¹  Jiajia Luo¹  Yuan Li¹  Zengyou Luo¹  Yingsa Huang¹ 

[1] Department of Preventive Medicine, School of Basic Medical Sciences, Henan University;Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Henan University;Kaifeng Key Laboratory of Cell Signal Transduction, Henan Provincial Engineering Center for Tumor Molecular Medicine;Bioinformatics Center, Institute of Biomedical Informatics, Henan University;Department of Pediatrics, First Clinical College, Harbin Medical University

关键词: pediatric obesity;    blood pressure;    arterial pressure;    sex;    China;   

DOI  :  10.3389/fped.2021.674504

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective: The objective of this study is to further explore the difference between elevated blood pressure (EBP), elevated pulse pressure (EPP), and elevated mean arterial pressure (EMAP) and obesity in Chinese school-age children by sex. Methods: We performed a cross-sectional study of 935 children between 7 and 12 years old. Overweight and obesity were defined by body mass index and body composition. The multivariate logistic regression and the adjusted population attributable risk were used to assess the effects of obesity on pre-EBP/EBP, EPP, and EMAP. The interactions were used to identify the modification of obese on the relationship between related indicators of blood pressure and height or age. Results: The average age of the children included in the study was 10. Boys with overweight and obesity had higher pre-EBP/EBP, EPP, and EMAP ( p 1]. Pre-EBP/EBP in 79% of boys and 76% of girls could be attributable to the visceral fat level. The interaction between BP, PP, MAP, and height or age was modestly increased in children with overweight and obesity, especially in boys. Conclusions: Independent of age and height, obesity not only increases blood pressure, it also increases mean arterial pressure and pulse pressure, and this effect is more pronounced in boys.

【 授权许可】

CC BY