期刊论文详细信息
Frontiers in Pediatrics | |
Case Report: The Use of Intravenous SMOFlipid Infusion to Treat Severe Asparaginase-Induced Hypertriglyceridemia in Two Pediatric Acute Lymphoblastic Leukemia Patients | |
article | |
Sie Chong Doris Lau1  C-Khai Loh1  Hamidah Alias1  | |
[1] Pediatric Hematology and Oncology Unit, Department of Pediatrics, UKM Medical Centre, Faculty of Medicine, The National University of Malaysia | |
关键词: acute lymphoblastic leukemia; asparaginase; hypertriglyceridemia; omega-3; SMOFlipid; pediatric; case report; | |
DOI : 10.3389/fped.2021.660627 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Frontiers | |
【 摘 要 】
Asparaginase-induced hypertriglyceridemia can have a spectrum of clinical presentations, from being asymptomatic to having life-threatening thrombosis or hyperviscosity syndrome. At present, there is no recommendation on routine lipid monitoring during asparaginase-containing treatment phase, nor a standardized guideline on its management. Two cases are presented here to illustrate the effects of concurrent infection on asparaginase-induced hypertriglyceridemia in patients with high-risk ALL and the use of SMOFlipid infusion as a treatment option in an acute situation.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO202108180003847ZK.pdf | 375KB | download |