Human Respiratory and Gut Microbiomes—Do They Really Contribute to Respiratory Health?

Frontiers in Pediatrics

article

Juliana Durack¹  Claus T. Christophersen³ 

[1] Symbiome Inc., United States;Division of Gastroenterology, Department of Medicine, University of California, United States;School of Medical and Health Sciences, Edith Cowan University;WA Human Microbiome Collaboration Centre, School of Molecular and Life Sciences, Curtin University

关键词: gut microbiome;    microbiome development;    asthma;    acute respiratory disease;    respiratory microbiome;   

DOI  :  10.3389/fped.2020.00528

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Human gastrointestinal and respiratory tracts are colonized by diverse polymicrobial communities shortly after birth, which are continuously molded by environmental exposure. The development of the resident microbiota in early life is a critical factor in the maturation of a healthy immune system. Disturbances to the intricate relationship between environmental exposure and maturation of the infant microbiome have been increasingly identified as a potential contributor to a range of childhood diseases. This review details recent evidence that implicates the contribution of gut and airway microbiome to pediatric respiratory health.

【 授权许可】

CC BY