Brainstem Auditory Evoked Potentials and Visual Potentials in Kawasaki Disease: An Observational Monocentric Study

Frontiers in Pediatrics

article

Maria Cristina Maggio¹  Giovanni Corsello¹  Giuseppe Salvo¹  Domenico Giuseppe Puma²  Rolando Cimaz³ 

[1] University Department PROMISE of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities “G. D'Alessandro”, University of Palermo;Pediatric Neuropsychiatry Operative Unit, Children Hospital “G. Di Cristina”;Department of Clinical Sciences and Community Health, University of Milan

关键词: kawasaki disease;    brainstem auditory evoked potentials;    visual evoked potentials;    coronary artery lesions;    intravenous immunoglobulins;   

DOI  :  10.3389/fped.2020.581780

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background: Kawasaki Disease is a systemic vasculitis, particularly involving coronary arteries. Rare involvement of other vascular districts is described, as central nervous system arteries, leading to a vasculitic neuropathy. Sensorineural hearing loss and alterations of evoked potentials are uncommonly reported complications. Methods: In an observational monocentric study, 59 children (37 males; 22 females; mean age: 2.7 ± 2.2 years) with documented Kawasaki Disease were enrolled. No risk factors for hearing loss and/or neurological impairment were identified in the cohort. Brainstem auditory evoked potentials and visual evoked potentials were correlated with clinical, hamatological and radiological data, evaluated in the acute phase of the Kawasaki Disease, and during the follow-up. Results: Evoked potentials were altered in 39/59 patients (66%): of these, 27/39 (69%) showed altered IV and V waves and/or III-V interwave latencies of brainstem auditory evoked potentials; 4/39 (10%) showed pathological visual evoked potentials; 8/39 (21%) had abnormalities of both brainstem auditory evoked potentials and visual evoked potentials. No permanent deafness was reported. Conclusion: Abnormalities in visual evoked potentials were not significantly correlated with coronary artery lesions; however, the presence of abnormalities of brainstem auditory evoked potentials were associated with the risk of coronary artery lesions.

【 授权许可】

CC BY