Echocardiographic Diagnosis and Hemodynamic Evaluation of Patent Ductus Arteriosus in Extremely Low Gestational Age Newborn (ELGAN) Infants

Frontiers in Pediatrics

article

Yogen Singh¹  Alain Fraisse³  Omer Erdeve⁵  Begum Atasay⁵ 

[1] Department of Pediatrics - Pediatric Cardiology and Neonatal Medicine, Cambridge University Hospitals NHS Foundation Trust, United Kingdom;University of Cambridge Clinical School of Medicine, United Kingdom;Pediatric Cardiology Services, Royal Brompton Hospital, United Kingdom;Imperial College London, National Heart and Lung Institute, United Kingdom;Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine

关键词: patent ductus arteriosus (PDA);    extreme preterm infants;    clinical decision making;    echocardiographic evaluation of PDA;    ELGAN extremely low gestational age newborn;   

DOI  :  10.3389/fped.2020.573627

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Persistent Patent ductus arteriosus (PDA) is a common finding in extremely low gestational age newborn infants and its prevalence is inversely proportional to the gestational age. The presence of a persistent PDA is associated with increased mortality and several significant morbidities including intraventricular hemorrhage, pulmonary hemorrhage, necrotizing enterocolitis, and chronic lung disease or bronchopulmonary dysplasia. However, treating PDA has not been demonstrated to have beneficial impact on the long term outcomes. Currently there is no consensus on whether to treat the PDA or not, and if treat, when to treat and how to treat. The echocardiography is the investigation of choice to diagnose PDA, estimating the magnitude of shunt volume and assessing its hemodynamic significance, and to exclude/diagnose any associated congenital heart defect before any intervention. Various echocardiographic parameters and staging/scoring systems have been described to help the clincians making the clinical decisions and some of theses scoring systems are quite complex to apply in a busy day to day clinical practice. This concised review paper is focused to help the clinicians in making a clinical decision based upon clincial and echocardiography parameters. Hence, only the parameters which are commonly used and helpful in making the clinical decisions in day to day clincial practice have been described in this paper.

【 授权许可】

CC BY