Extremely Preterm Infants Have a Higher Fat Mass Percentage in Comparison to Very Preterm Infants at Term-Equivalent Age

Frontiers in Pediatrics

article

Marlies Bruckner¹  Zahra Khan²  Christoph Binder³  Nicholas Morris¹  Bernadette Windisch¹  Sandra Holasek⁴  Berndt Urlesberger¹ 

[1] Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz;Department of Food Science and Human Nutrition, University of Veterinary and Animal Sciences;Division of Neonatology, Pediatric Intensive Care Medicine and Neuropediatrics, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna;Division of Immunology and Pathophysiology, Otto Loewi Research Centre, Medical University Graz

关键词: nutrition;    body composition;    air displacement plethysmography;    PEA POD;    preterm;    fat mass;    weight percentile;    gestational age;   

DOI  :  10.3389/fped.2020.00061

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background: Early nutritional support of preterm infants is important because it influences long-term health and development. Body composition has an influence on cardiovascular disease, metabolic syndrome, and neurocognitive outcome in the long term. Objective: To assess body composition in preterm infants <32 weeks of gestation at term-equivalent age and to analyze the influence of an optimized nutritional approach. Methods: This is a prespecified secondary outcome analysis of a prospective observational study comparing the body composition in regard to gestational age. The preterm infants were classified according to gestational age as extremely preterm infants (<28 weeks gestation at birth) and very preterm infants (≥28 weeks gestation at birth) and according to weight percentile as appropriate for gestational age and small for gestational age. Body composition was determined by air displacement plethysmography using the PEA POD. The preterm infants obtained nutrition according to the ESPGHAN 2010 Guidelines. Results: Seventy-four preterm infants were analyzed. The mean (SD) gestational age was 28.7 (2.4) weeks, and birth weight was 1,162 (372) g. Fat mass percentage was significantly higher in extremely preterm infants in comparison to very preterm infants [17.0, 95% confidence interval (CI) 15.9–18.1 vs. 15.5, 95% CI 14.7–16.2]. There was no significant difference of fat mass percentage according to weight percentiles. Conclusions: Extremely preterm infants had a significantly higher fat mass percentage compared to very preterm infants at term-equivalent age. There was no significant difference of fat mass percentage according to weight percentiles.

【 授权许可】

CC BY