Frontiers in Pediatrics | |
The Incidence of Paediatric Acute Kidney Injury Identified Using an AKI E-Alert Algorithm in Six English Hospitals | |
article | |
Sheetal Bhojani1  Manish D. Sinha2  David V. Milford4  Jelena Stojanovic2  Nabil Melhem2  Heather Maxwell1  Peter Houtman5  Angela Hall5  Cheentan Singh6  Wesley Hayes7  Rachel Lennon8  | |
[1] Royal Hospital for Children, United Kingdom;Evelina London Children's Hospital, United Kingdom;Kings College London, United Kingdom;Birmingham Women's and Children's Hospital, United Kingdom;Leicester Royal Infirmary, United Kingdom;North Middlesex University Hospital NHS Trust, United Kingdom;Bristol Royal Hospital for Children, United Kingdom;Royal Manchester Children's Hospital, United Kingdom | |
关键词: acute kidney injury; hospital; epidemiology; alerts; algorithm; | |
DOI : 10.3389/fped.2020.00029 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Frontiers | |
【 摘 要 】
Objective: Acute kidney injury (AKI) is a significant cause of morbidity and mortality among hospitalised patients. The objectives in this study were (i) to investigate the incidence of AKI using the National Health Services (NHS) AKI e-alert algorithm as a means of identifying AKI; and (ii) in a randomly selected sub-group of children with AKI identified using the algorithm, to evaluate the recognition and management of AKI. Patients and Methods: Retrospective cross-sectional study with initial electronic retrieval of creatinine measurements at six hospitals in England over a six-month period. Results were evaluated using the NHS AKI e-alert algorithm with recognition and management of AKI stages 1, 2 and 3 reviewed in a sub-set of randomly selected patient case notes. Patients aged 29 to 17 years were included. AKI stage 1 was defined as a rise of 1.5 – ≤2x baseline creatinine level; AKI stage 2 a rise of ≤ 2.0 and < 3.0; AKI stage 3 a rise of ≥ 3.0. Urine output was not considered for AKI staging. Results: 57,278 creatinine measurements were analysed. 5,325 (10.8%) AKI alerts were noted in 1,112 patients with AKI 1 (62%), AKI 2 (16%) and AKI 3 (22%). There were 222 (20%) <1y, 432 (39%) 1 ≤ 6y, 192 (17%) 6 ≤ 11y, 207 (19%) 11 ≤ 16y, and 59 (5%) 16–17y. Case notes of 123 of 1,112 [11.1%] children with AKI alerts were reviewed. Confirmed AKI was recognised with a documented management plan following its identification in n = 32 [26%] patients only. Conclusions: In this first multicentre study of the incidence of AKI in children admitted to selected hospitals across England, the incidence of AKI was 10.8% with most patients under the age of 6 years and with AKI stage 1. Recognition and management of AKI was seen in just over 25% children. These data highlight the need to improve recognition of AKI in hospitalised children in the UK.
【 授权许可】
CC BY
【 预 览 】
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