Cancer Risk in Pediatric-Onset Inflammatory Bowel Disease

Frontiers in Pediatrics

article

Wael El-Matary¹  Charles N. Bernstein⁴ 

[1] Department of Pediatrics, University of Manitoba;Children's Hospital Research Institute of Manitoba;IBD Clinical and Research Center, University of Manitoba;Department of Internal Medicine, University of Manitoba

关键词: cancer;    colitis;    Crohn;    inflammatory bowel disease;    IBD;    malignancy;    pediatric;   

DOI  :  10.3389/fped.2020.00400

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Inflammatory bowel disease (IBD) is a chronic, immune-mediated, non-curable disease. The incidence of IBD appears to have risen over the last few decades especially in the pediatric age group. IBD usually presents with gastrointestinal symptoms, including abdominal pain, diarrhea, and bleeding per rectum but can also be associated with systemic symptoms such as weight loss, fatigue, joint and skin problems, and psychological comorbidities. One major complication is gastrointestinal and extra-intestinal malignancy. This review discusses literature that focuses on cancer risk of pediatric-onset IBD.

【 授权许可】

CC BY