Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment

Frontiers in Medicine

article

Denise Rotta¹  Maurizio Rossini¹  Alessandro Giollo¹  Ombretta Viapiana¹  Giovanni Orsolini¹  Eugenia Bertoldo¹  Davide Gatti¹  Giovanni Adami¹ 

[1] Rheumatology Unit, University of Verona

关键词: osteoporosis;    rheumatoid arthritis;    psoriatic arthritis;    spondyloarthritis;    fractures;    bone mineral density;   

DOI  :  10.3389/fmed.2020.613720

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflammatory arthritides, especially Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritides, as well as the effect of anti-rheumatic treatments and anti-osteoporotic medication on bone health and fracture incidence, including recent data on novel therapeutic perspective.

【 授权许可】

CC BY