Clinical and Pathological Study of Tumor Border Invasion—Is Narrow Resection Margin Acceptable in Hepatoblastoma Surgery?

Frontiers in Medicine

article

Gang Shen¹  Linlin Wu¹  Jie Zhao³  Bin Wei⁴  Xianjun Zhou¹  Feifei Wang³  Jie Liu¹  Qian Dong¹ 

[1] Department of Pediatric Surgery, The Affiliated Hospital of Qingdao University;Department of Pediatric Surgery, Weifang People's Hospital;Pathology Group of Shandong Key Laboratory of Digital Medicine and Computer Assisted Surgery, The Affiliated Hospital of Qingdao University;Shandong College Collaborative Innovation Center of Digital Medicine in Clinical Treatment and Nutrition Health

关键词: hepatoblastoma;    border;    invasion;    pathology;    chemotherapy;   

DOI  :  10.3389/fmed.2020.00059

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Aim: We aim to study clinically and pathologically whether narrow resection margin (1 cm) and narrow resection margin (<1 cm) of the two groups. Pathologically, the tumor of all 42 patients had capsules surrounding the tumor. Of the patients in Group 1 (without preoperative CHT), 9% (2/22) had micrometastatic cancer nests outside the capsule, and the farthest distance from the cancer nests to the capsule was 4.6 mm. Of the patients in Group 2 (with preoperative CHT), 75% (15/20) showed residual cancer nests in the paratumor liver tissue, and the farthest distance was 9.6 mm; three and two cases, respectively, showed extracapsular intravascular microtumorous thrombi. Conclusion: Clinically and pathologically, narrow resection margin is acceptable in hepatoblastoma surgery.

【 授权许可】

CC BY