Commentary: Vitamin C supplementation for prevention and treatment of pneumonia

Frontiers in Medicine

article

Harri Hemilä¹  Elizabeth Chalker² 

[1] Department of Public Health, University of Helsinki;School of Public Health, University of Sydney

关键词: ascorbic acid;    meta-analysis;    pneumonia;    respiratory tract infections;    statistics;   

DOI  :  10.3389/fmed.2020.595988

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

In the early literature, vitamin C deficiency was associated with pneumonia (1–3). In a 1979 trial, Pitt and Costrini reported just one case of pneumonia in US Marines administered vitamin C, but seven cases in the placebo group, and concluded that “no claim of a beneficial effect of vitamin C in preventing viral or bacterial pneumonia should be made on the basis of this study, although this certainly should be an area for further investigation” (4). Two decades later, Hemilä carried out a meta-analysis of three controlled trials assessing the influence of vitamin C on the risk of contracting pneumonia, and concluded that “the considerably lower pneumonia incidence in the vitamin C groups indicates that further work should be performed to address the question of whether vitamin C affects susceptibility to pneumonia more explicitly” (5).

【 授权许可】

CC BY