Acute Functional Outcomes in Critically Ill COVID-19 Patients

Frontiers in Medicine

article

Matthew Rong Jie Tay¹  Poo Lee Ong¹  Ser Hon Puah²  Shuen Loong Tham¹ 

[1] Department of Rehabilitation Medicine, Tan Tock Seng Hospital;Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital

关键词: SARS-CoV-2;    critical illness;    coronavirus;    acute respiratory distress syndrome;    dependent ambulation;    intensive care units;    dyspnea;    muscle weakness;   

DOI  :  10.3389/fmed.2020.615997

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background: COVID-19 (Coronavirus Disease 2019) is a global cause of morbidity and mortality currently. We aim to describe the acute functional outcomes of critically ill coronavirus disease 2019 (COVID-19) patients after transferring out of the intensive care unit (ICU). Methods: 51 consecutive critically ill COVID-19 patients at a national designated center for COVID-19 were included in this exploratory, retrospective observational cohort study from January 1 to May 31, 2020. Demographic and clinical data were collected and analyzed. Functional outcomes were measured primarily with the Functional Ambulation Category (FAC), and divided into 2 categories: dependent ambulators (FAC 0–3) and independent ambulators (FAC 4–5). Multivariate analysis was performed to determine associations. Results: Many patients were dependent ambulators (47.1%) upon transferring out of ICU, although 92.2% regained independent ambulation at discharge. On multivariate analysis, we found that a Charlson Comorbidity Index of 1 or more (odds ratio 14.02, 95% CI 1.15–171.28, P = 0.039) and a longer length of ICU stay (odds ratio 1.50, 95% CI 1.04–2.16, P = 0.029) were associated with dependent ambulation upon discharge from ICU. Conclusions: Critically ill COVID-19 survivors have a high level of impairment following discharge from ICU. Such patients should be screened for impairment and managed appropriately by rehabilitation professionals, so as to achieve good functional outcomes on discharge.

【 授权许可】

CC BY