Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness

Frontiers in Medicine

article

Shannon L. Delaney¹  Lilly A. Murray¹  Claire E. Aasen¹  Clair E. Bennett¹  Ellen Brown¹  Brian A. Fallon¹ 

[1] Lyme & Tick-Borne Diseases Research Center, Columbia University Irving Medical Center, United States;New York State Psychiatric Institute, Columbia University Irving Medical Center, United States

关键词: Borrelia miyamotoi disease;    relapsing fever borrelia;    Lyme disease;    serodiagnosis;    post-treatment Lyme disease syndrome;    borreliosis;   

DOI  :  10.3389/fmed.2020.567350

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on the GlpQ IgG ELISA. Nearly all of the patients (98%) had no prior B. miyamotoi testing, indicating that clinicians rarely test for this emerging tick-borne pathogen. Compared to patients who solely tested positive for Lyme disease antibodies, patients with B. miyamotoi antibodies presented with significantly more sleepiness and pain. A prospective study is needed to ascertain the relationship between the presence of B. miyamotoi antibodies and persistent symptoms.

【 授权许可】

CC BY