Granulomatous Sarcoidosis Mimics

Frontiers in Medicine

article

Marc A. Judson¹ 

[1]Division of Pulmonary and Critical Care Medicine MC-91, Department of Medicine, United States

关键词: sarcoidosis;    diagnosis;    mimics;    granuloma;    drug reaction;    infection;    vasculitis;   

DOI  :  10.3389/fmed.2021.680989

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Many granulomatous diseases can mimic sarcoidosis histologically and in terms of their clinical features. These mimics include infectious granulomatous diseases, granulomatous reactions to occupational and environmental exposures, granulomatous drug reactions, vasculitides and idiopathic granulomatous conditions. It is important to distinguish sarcoidosis from these mimics, as a misdiagnosis of these diseases may have serious consequences. This manuscript reviews numerous sarcoidosis mimics and describes features of these diseases that may allow them to be differentiated from sarcoidosis. Distinguishing features between sarcoidosis and its mimics requires a careful review of the medical history, symptoms, demographics, radiographic findings, histologic features, and additional laboratory data. Understanding the clinical characteristics of sarcoidosis and its mimics should lead to more accurate diagnoses and treatment of granulomatous disorders that should improve the care of these patients. As the diagnostic criteria of sarcoidosis are not standardized, it is possible that some of these sarcoidosis mimics may represent varied clinical presentations of sarcoidosis itself.

【 授权许可】

CC BY