Stakeholder Perspectives on Advancing Understanding of Prenatal Opioid Exposure and Brain Development From the iOPEN Consortium of the Healthy Brain and Child Development Study

Frontiers in Psychology

article

Jennifer L. DiPietro¹  Tessa C. Vatalaro²  Moriah E. Thomason²  Elinor L. Sullivan¹  Alice M. Graham¹  Kristen L. Mackiewicz Seghete¹  Elizabeth E. Krans⁵  Kasey Edwards Snider¹  Reina Bower⁷  Kea Parker⁸  Janie Gullickson⁷  Alexandra S. Potter⁹  Hugh Garavan⁹ 

[1] Department of Psychiatry, Oregon Health and Science University, United States;Department of Child and Adolescent Psychiatry, New York University Medical Center, United States;Department of Population Health, New York University Medical Center, United States;Department of Behavioral Neuroscience, Oregon Health and Science University, United States;Department of Obstetrics, and Reproductive Sciences, University of Pittsburgh, United States;Magee-Women's Research Institute and Foundation, United States;Mental Health Addiction Association of Oregon, United States;Department of Family Medicine, Oregon Health and Science University, United States;Department of Psychiatry, University of Vermont, United States

关键词: stakeholders;    patient advocates;    opioids;    addiction;    pregnancy;    in utero exposure;    neurodevelopment;    Healthy Brain and Child Development Study;   

DOI  :  10.3389/fpsyg.2021.698766

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Introduction: There is a dire need for research regarding the implications of opioid use during pregnancy on fetal and childhood development to better inform both medical practice and policy. The Healthy Brain and Child Development Study will examine brain and behavioral development from birth through the first decade of life. Due to large scope and anticipated complexity of this initiative, an 18-month planning phase was implemented across 28 sites across the nation. A core element of the Phase I initiative involved the development of Stakeholder Advisory Committees to inform the next phase of the initiative. Methods: Phase I stakeholder meetings were conducted at Oregon Health and Science University, New York University Langone Medical Center, the University of Pittsburgh, and the University of Vermont to better understand perspectives and inform upcoming research. Despite differences in the structure of the stakeholder meetings by site, the overarching goals for the meetings included establishing relationships, gathering input, and learning about research engagement. Documents from each meeting were reviewed for location, duration, attendees, common research themes, and pertinent suggestions for improving research approaches. Results: All stakeholders had high levels of interest in research for pregnant people with substance use disorders and agreed on research priorities including collaboration, connection, communication, and support. Different stakeholders offered unique perspectives on various aspects of study design and themes that emerged through meetings. Discussion: Overall, there was excitement about the research, especially the opportunity to include the voices of people with lived experience; collaboration between providers, peer support specialists, patients, and others; and excitement around contributing to research that could elucidate new and pertinent findings in the realm of addiction medicine and child development. Sites also found that there is mistrust between people with substance use disorder and the medical system, and this could be addressed by including people with lived experience on the research team, forming connections, communicating clearly, training the research team in implicit bias, and practicing trauma-informed care. In conclusion, these stakeholder meetings provided valuable information for structuring upcoming studies; however, researchers would have benefitted from more time and more opportunities for in-person connection.

【 授权许可】

CC BY